Holland, M. L., Groth, S. W., Smith, J. A., Meng, Y., & Kitzman, H. (2018). Low birthweight in second children after nurse home visiting. Journal of Perinatology, 38(12), 1610–1619.

Citation Year
Used in Implementation Reports
Study Participants

The study sample consisted of 512 triads (mother, firstborn child, and second-born child): 355 triads in the comparison group and 157 triads in the treatment group. This study focused on outcomes related to the second-born child. The study participants were all participants in a larger randomized controlled trial (RCT). To be eligible for the original RCT, women had to be primiparous and demonstrate two of three risk factors: unmarried, unemployed, and not graduated from high school. Those with known chronic conditions associated with poor birth outcomes were not eligible to participate. At baseline, participants tended to be young (about 18 years old on average), low-income (discretionary income was $1,283 for the comparison group and $15 for the treatment group, on average), and African American.


Memphis, Tennessee

Home Visiting Services

Mothers in the treatment group received home visits from nurses who provided support and education aimed at improving maternal health and first pregnancy outcomes, child health and development, and family economic self-sufficiency. Home visits varied from weekly to monthly from the initial pregnancy to the childs second birthday. Mothers in the treatment group also received the services that mothers in the comparison group received.

Comparison Conditions

Mothers in the comparison group did not receive NFP home visiting services, but did receive transportation to prenatal care and early childhood developmental screening and referral services until the child was 2 years old.

Staff Characteristics and Training

Not described

Author Affiliation

None of the study authors are developers of this model.

Funding Sources

University of Rochester CTSA award number TL1 TR002000 from the National Center for Advancing Translational Sciences of the National Institutes of Health.

Study Reg

Clinicaltrials.gov Identifier: None found. Study registration was assessed by HomVEE beginning with the 2014 review.

Not applicable
Not applicable
Confounding Factors
Baseline Equivalence
Established on race/ethnicity and SES; outcomes not feasible to assess at baseline
Screening Decision
Passes screens