Izzo, C., Eckenrode, J., Smith, E., Henderson, C., Cole, R., Kitzman, H., & Olds, D. L. (2005). Reducing the impact of uncontrollable stressful life events through a program of nurse home visitation for new parents. Prevention Science, 6(4), 269–274.
| Screening decision | Screening conclusion |
|---|---|
| Passes screens | Eligible for review |
| Rating | Design | Attrition | Baseline equivalence | Reassignment | Confounding factors |
|---|---|---|---|---|---|
| High | Randomized controlled trial | Low | Established on race/ethnicity and SES; outcomes not feasible to assess at baseline | None | None |
In addition to the outcomes that received a high rating, substance use outcomes in the maternal health domain received a moderate rating because equivalence was not established on baseline measures of the outcomes.
| Study participants | Participants were 324 mothers and 315 of their first-born children. The mothers and children all participated in an RCT examining the Nurse-Family Partnership model in Elmira, NY in 1978. At the time of recruitment, participants were pregnant, first-time mothers who were less than 25 weeks pregnant. All participants were all either under the age of 19; unmarried; or had low socioeconomic status, as indicated by their Medicaid eligibility. |
|---|---|
| Setting | Elmira, NY, USA |
| Intervention services | The treatment group received in-home nurse visits from pregnancy through 24 months after birth, in addition to the same services as the comparison group. |
| Comparison conditions | Mothers in the comparison group received developmental and sensory screening for their children, clinical referrals, and transportation to prenatal and postnatal care. |
| Staff characteristics and training | Services were provided by registered nurses. |
| Funding sources | This study was supported with grants from the Prevention Research Branch of the National Institutes of Mental Health (R01-MH49381); the Assistant Secretary for Planning and Evaluation, U.S. Department of Health and Human Services (96ASPE278A); the Children's Bureau, U.S. Department of Health and Human Services (90-CA-1631). The research was also supported by an NIH Senior Research Scientist Award. |
| Author affiliation | David L. Olds, one of the study authors, is also the model developer. |
Clinicaltrials.gov Identifier: None found. Study registration was assessed by HomVEE beginning with the 2014 review.
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Mental health - Anxiety: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 mothers | Unadjusted mean = 2.56 | Unadjusted mean = 2.56 | MD = 0.00 | HomeVEE calculated = 0.00 | Not statistically significant, p = 1.00 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Mental health - Depression: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 mothers | Unadjusted mean = 2.01 | Unadjusted mean = 2.02 | MD = -0.01 | HomeVEE calculated = -0.01 | Not statistically significant, p = 0.95 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Mental health - Emotional stability: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 mothers | Unadjusted mean = 3.75 | Unadjusted mean = 3.74 | MD = 0.01 | HomeVEE calculated = 0.02 | Not statistically significant, p = 0.90 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Mental health - Positive well-being: Mental Health Inventory (MHI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 mothers | Unadjusted mean = 3.78 | Unadjusted mean = 3.79 | MD = -0.01 | HomeVEE calculated = -0.02 | Not statistically significant, p = 0.90 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| Moderate | Alcohol impairment score | FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 15 years | 300 mothers | Unadjusted mean = 0.35 | Unadjusted mean = 0.37 | MD = -0.02 | HomeVEE calculated = -0.02 | Not statistically significant, p = 0.87 | HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| Moderate | Substance use - # cigarettes smoked per day | FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 15 years | 300 mothers | Unadjusted mean = 8.32 | Unadjusted mean = 10.56 | MD = -2.24 | HomeVEE calculated = -0.21 | Not statistically significant, p = 0.11 | HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| Moderate | Substance use - binge drinking: # days had 5+ drinks in the past year | FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample | 15 years | 300 mothers | Unadjusted mean = 11.70 | Unadjusted mean = 9.27 | MD = 2.43 | HomeVEE calculated = 0.06 | Not statistically significant, p = 0.65 | HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| Rating | Outcome measure | Effect | Sample | Timing of follow-up | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Parenting practices - Hostility: Child Report of Parental Behavior Inventory (CRPBI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 children | Unadjusted mean = 1.38 | Unadjusted mean = 1.99 | MD = -0.61 | HomeVEE calculated = -1.22 | Statistically significant, p = 0.00 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. Negative effect is favorableNegative effect is favorable to the intervention. |
| High | Parenting practices - Inconsistent discipline: Child Report of Parental Behavior Inventory (CRPBI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 children | Unadjusted mean = 1.90 | Unadjusted mean = 1.99 | MD = -0.09 | HomeVEE calculated = -0.16 | Not statistically significant, p = 0.23 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Parenting practices - Parent involvement: Child Report of Parental Behavior Inventory (CRPBI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 children | Unadjusted mean = 3.34 | Unadjusted mean = 3.33 | MD = 0.01 | HomeVEE calculated = 0.02 | Not statistically significant, p = 0.89 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Parenting practices - Supervision: Parenting Style Index measure by Steinberg et al. (1993) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 children | Unadjusted mean = 0.86 | Unadjusted mean = 0.89 | MD = -0.03 | HomeVEE calculated = -0.26 | Not statistically significant, p = 0.05 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| High | Parenting practices - Warmth: Child Report of Parental Behavior Inventory (CRPBI) |
FavorableUnfavorable or ambiguousNo Effect |
Nurse-visited group 4 vs. comparison groups 1 and 2, Elmira sample |
15 years |
300 children | Unadjusted mean = 3.65 | Unadjusted mean = 3.67 | MD = -0.02 | HomeVEE calculated = -0.04 | Not statistically significant, p = 0.76 |
HomVEE calculated significanceStatistical significance is based on HomVEE calculations. |
| Outcome measure | Description of measure | Data collection method | Properties of measure |
|---|---|---|---|
Mental health - Anxiety: Mental Health Inventory (MHI) |
The RAND Mental Health Inventory (MHI) Survey consists of 37 measures of respondent core functioning and well-being. |
Parent report |
Properties not reported by author. |
Mental health - Depression: Mental Health Inventory (MHI) |
The RAND Mental Health Inventory (MHI) Survey consists of 37 measures of respondent core functioning and well-being. |
Parent report |
Properties not reported by author. |
Mental health - Emotional stability: Mental Health Inventory (MHI) |
The RAND Mental Health Inventory (MHI) Survey consists of 37 measures of respondent core functioning and well-being. |
Parent report |
Properties not reported by author. |
Mental health - Positive well-being: Mental Health Inventory (MHI) |
The RAND Mental Health Inventory (MHI) Survey consists of 37 measures of respondent core functioning and well-being. |
Parent report |
Properties not reported by author. |
| Alcohol impairment score | Not reported |
Not reported |
Properties not reported by author. |
Substance use - # cigarettes smoked per day |
Mothers in the study were asked to report the number of cigarettes they smoked per day in the past year. |
Parent report |
Properties not reported by author. |
Substance use - binge drinking: # days had 5+ drinks in the past year |
Mothers in the study were asked to report how many times in the past year they'd consumed at least five drinks in a single drinking episode. |
Parent report |
Properties not reported by author. |
| Outcome measure | Description of measure | Data collection method | Properties of measure |
|---|---|---|---|
Parenting practices - Hostility: Child Report of Parental Behavior Inventory (CRPBI) |
The Child Report of Parental Behavior Inventory (CRPBI) is designed to assess parenting behavior based on child and parent reports. |
Child report |
Properties not reported by author. |
Parenting practices - Inconsistent discipline: Child Report of Parental Behavior Inventory (CRPBI) |
The Child Report of Parental Behavior Inventory (CRPBI) is designed to assess parenting behavior based on child and parent reports. |
Child report |
Properties not reported by author. |
Parenting practices - Parent involvement: Child Report of Parental Behavior Inventory (CRPBI) |
The Child Report of Parental Behavior Inventory (CRPBI) is designed to assess parenting behavior based on child reports. |
Child report |
Properties not reported by author. |
Parenting practices - Supervision: Parenting Style Index measure by Steinberg et al. (1993) |
The Parenting Style Index is a measure developed by Steinberg and colleagues in 1993, in part to assess personal communication between parents and children. |
Child report |
Properties not reported by author. |
Parenting practices - Warmth: Child Report of Parental Behavior Inventory (CRPBI) |
The Child Report of Parental Behavior Inventory (CRPBI) is designed to assess parenting behavior based on child and parent reports, using psychometric measures. |
Child report |
Properties not reported by author. |
