Manuscript Detail

View Revisions

Olds, D. L., Robinson, J., Pettitt, L., Luckey, D. W., Holmberg, J., Ng, R. K., et al. (2004). Effects of home visits by paraprofessionals and by nurses: Age 4 follow-up results of a randomized trial. Pediatrics, 114(6), 1560-1568.

Manuscript screening details
Screening decision Screening conclusion HomVEE procedures and standards version
Passes screens Eligible for review Version 1
Study design details
Rating Design Attrition Baseline equivalence Compromised randomization Confounding factors Valid, reliable measure(s)
High Randomized controlled trial Low No relevant differences for nurse home visitor group. Statistically significant different in income between paraprofessional home visitor and comparison group. None None Not assessed in manuscripts reviewed before 2021
Notes:

In 2020, HomVEE updated this review to remove eight mother's partnership status/family structure findings from the Family Economic Self-Sufficiency domain because ACF determined that mother's partnership status is ineligible for review by HomVEE.

footnote160

Submitted by user on

This study includes three groups: nurse home visits, paraprofessional home visits, and a comparison group. The high rating is based on the comparison between nurse home visits and the comparison group. The comparison between the paraprofessional and comparison groups receives a moderate rating because of a statistically significant difference in income at baseline that was not controlled.

Study characteristics
Study participants Women were recruited through 21 antepartum clinics that served low-income pregnant women. Recruitment focused on women who had no previous live births and either qualified for Medicaid or had no private health insurance. Between March 1994 and June 1995, 1,178 women were invited to participate and 735 consented and were randomly assigned to one of three conditions: a control group, nurse home visiting, and paraprofessional home visiting. Randomization was conducted within strata based on maternal race (Hispanic, white, black, American Indian, or Asian), maternal gestational age (less than 32 weeks, 32 weeks or more), and geographic region. This study measured the sample when the children were 4 years old. The sample of women who completed the interviews when children were 4 years old included 635 women, 204 in the nurse home visiting program group, 211 in the paraprofessional home visiting program group, and 220 in the comparison group.
Setting Denver, Colorado metropolitan area
Intervention services The study included two program groups: one serviced by paraprofessionals and one serviced by nurses. Women assigned to both groups received developmental screening and referral services for their children and home visits during pregnancy and infancy (until the child was 2 years old). Both groups had the same goals: (1) to improve women’s health-related behavior, (2) to support parents in providing competent care, and (3) to encourage planning future pregnancies and promote education and employment. Paraprofessionals conducted 6.3 home visits on average during pregnancy and 16 visits during infancy. Nurses conducted 6.5 home visits on average during pregnancy and 21 visits during infancy.
Comparison conditions Women in the comparison group received developmental screening and referral services for their children at 6, 12, 15, 21, and 24 months.
Subgroups examined This field lists subgroups examined in the manuscript (even if they were not replicated in other samples and not reported on the summary page for this model’s report).

• Mother has psychological vulnerability (yes or no)

Funding sources The Colorado Trust (grant 99030); the Administration for Children and Families, Department of Health and Human Services (grant 90PD0232); and a Senior Research Scientist Award (grant 1-K05-MH01382-01) to D.L.O.
Author affiliation David L. Olds, a study author, is a developer of this model.
Peer reviewed Peer reviewed status is not listed for manuscripts reviewed before 2021.

Findings that rate moderate or high

Child development and school readiness
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High Emotional regulation in testing
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Nurse home visitors and comparison (Denver) 4-year follow-up 144 children Adjusted mean = 99.54 Adjusted mean = 98.42 Mean difference = 1.12 Study reported = 0.11 Not statistically significant,
p = 0.51

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High PLS-3 (Total language score)
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Nurse home visitors and comparison (Denver) 4-year follow-up 144 children Adjusted mean = 91.39 Adjusted mean = 86.73 Mean difference = 4.66 Study reported = 0.31 Statistically significant,
p = 0.04

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Behavioral adaptation in testing
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Nurse home visitors and comparison (Denver) 4-year follow-up 144 children Adjusted mean = 100.41 Adjusted mean = 96.66 Mean difference = 3.75 Study reported = 0.38 Statistically significant,
p = 0.04

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Executive function composite
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Nurse home visitors and comparison (Denver) 4-year follow-up 144 children Adjusted mean = 100.16 Adjusted mean = 95.48 Mean difference = 4.68 Study reported = 0.47 Statistically significant,
p = 0.00

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Externalizing behavior problems
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Nurse home visitors and comparison (Denver) 4-year follow-up 144 children Adjusted mean = 13.16 Adjusted mean = 12.95 Mean difference = 0.21 Study reported = 0.03 Not statistically significant,
p = 0.88

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High PLS-3 (Total language score)
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Paraprofessional home visitors and comparison (Denver) 4-year follow-up 163 children Adjusted mean = 90.09 Adjusted mean = 86.73 Mean difference = 3.36 Study reported = 0.23 Not statistically significant,
p = 0.13

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Behavioral adaptation in testing
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Paraprofessional home visitors and comparison (Denver) 4-year follow-up 163 children Adjusted mean = 99.51 Adjusted mean = 96.66 Mean difference = 2.85 Study reported = 0.28 Not statistically significant,
p = 0.10

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Emotional regulation in testing
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Paraprofessional home visitors and comparison (Denver) 4-year follow-up 163 children Adjusted mean = 99.29 Adjusted mean = 98.42 Mean difference = 0.87 Study reported = 0.09 Not statistically significant,
p = 0.59

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Executive function composite
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Paraprofessional home visitors and comparison (Denver) 4-year follow-up 163 children Adjusted mean = 98.40 Adjusted mean = 95.48 Mean difference = 2.92 Study reported = 0.29 Not statistically significant,
p = 0.06

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Externalizing behavior problems
FavorableUnfavorable or ambiguousNo Effect
Mothers with low psychological resources — Paraprofessional home visitors and comparison (Denver) 4-year follow-up 163 children Adjusted mean = 12.91 Adjusted mean = 12.95 Mean difference = -0.04 Study reported = 0.00 Not statistically significant,
p = 0.98

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High PLS-3 (total language score)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 children Adjusted mean = 92.65 Adjusted mean = 92.01 Mean difference = 0.64 Study reported = 0.04 Not statistically significant,
p = 0.65

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Behavioral adaptation in testing
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 children Adjusted mean = 99.63 Adjusted mean = 99.71 Mean difference = -0.08 Study reported = -0.01 Not statistically significant,
p = 0.93

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Child attended Head Start, preschool, center-based day care, or government-supported family care
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.54 = 0.66 OR = 0.62 HomVEE calculated = -0.29 Statistically significant,
p = 0.03

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Emotional regulation in testing
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 children Adjusted mean = 99.54 Adjusted mean = 99.61 Mean difference = -0.07 Study reported = -0.01 Not statistically significant,
p = 0.95

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Executive function composite
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 children Adjusted mean = 100.64 Adjusted mean = 99.69 Mean difference = 0.95 Study reported = 0.09 Not statistically significant,
p = 0.34

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

High Externalizing behavior problems
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 children Adjusted mean = 12.16 Adjusted mean = 12.20 Mean difference = -0.04 Study reported = -0.01 Not statistically significant,
p = 0.96

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate PLS-3 (total language score)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 children Adjusted mean = 93.24 Adjusted mean = 92.01 Mean difference = 1.23 Study reported = 0.08 Not statistically significant,
p = 0.39

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate Behavioral adaptation in testing
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 children Adjusted mean = 100.66 Adjusted mean = 99.71 Mean difference = 0.95 Study reported = 0.09 Not statistically significant,
p = 0.34

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate Child attended Head Start, preschool, center-based day care, or government-supported family care
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 children = 0.59 = 0.66 OR = 0.76 HomVEE calculated = -0.17 Not statistically significant,
p = 0.21

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate Emotional regulation in testing
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 children Adjusted mean = 100.86 Adjusted mean = 99.61 Mean difference = 1.25 Study reported = 0.13 Not statistically significant,
p = 0.21

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate Executive function composite
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 children Adjusted mean = 99.70 Adjusted mean = 99.69 Mean difference = 0.01 Study reported = 0.00 Not statistically significant,
p = 1.00

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Moderate Externalizing behavior problems
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 children Adjusted mean = 11.65 Adjusted mean = 12.20 Mean difference = -0.55 Study reported = -0.08 Not statistically significant,
p = 0.44

footnote5

Submitted by user on

Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Child health
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High Subsequent low birth weight newborns
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.06 = 0.08 OR = 0.75 HomVEE calculated = -0.17 Not statistically significant,
p = 0.45
High Subsequent special care admissions
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.06 = 0.08 OR = 0.66 HomVEE calculated = -0.26 Not statistically significant,
p = 0.27
Moderate Subsequent special care admissions
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.05 = 0.08 OR = 0.54 HomVEE calculated = -0.38 Not statistically significant,
p = 0.13
Moderate Subsequent low birth weight newborns
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional. home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.03 = 0.08 OR = 0.34 HomVEE calculated = -0.64 Statistically significant,
p = 0.03
Family economic self-sufficiency
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High Graduated from high school or earned GED
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.80 = 0.76 OR = 1.26 HomVEE calculated = 0.14 Not statistically significant,
p = 0.35
High Months mother employed (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 14.42 Adjusted mean = 13.38 Mean difference = 1.04 Study reported = 0.04 Not statistically significant,
p = 0.22
High Months of AFDC (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 1.88 Adjusted mean = 2.10 Mean difference = -0.22 Study reported = 0.01 Not statistically significant,
p = 0.69
High Months of food stamps (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 4.32 Adjusted mean = 3.98 Mean difference = 0.34 Study reported = 0.07 Not statistically significant,
p = 0.67
High Months of Medicaid (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 7.34 Adjusted mean = 6.98 Mean difference = 0.36 Study reported = -0.03 Not statistically significant,
p = 0.71
Moderate Graduated from high school or earned GED
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.82 = 0.76 OR = 1.39 HomVEE calculated = 0.20 Not statistically significant,
p = 0.18
Moderate Months mother employed (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 15.13 Adjusted mean = 13.38 Mean difference = 1.75 Study reported = 0.11 Statistically significant,
p = 0.04
Moderate Months of AFDC (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 1.95 Adjusted mean = 2.10 Mean difference = -0.15 Study reported = -0.19 Not statistically significant,
p = 0.78
Moderate Months of food stamps (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 4.56 Adjusted mean = 3.98 Mean difference = 0.58 Study reported = 0.21 Not statistically significant,
p = 0.47
Moderate Months of Medicaid (25–48 months postpartum)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 8.08 Adjusted mean = 6.98 Mean difference = 1.10 Study reported = 0.02 Not statistically significant,
p = 0.26
Maternal health
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High MHI
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 99.82 Adjusted mean = 99.16 Mean difference = 0.66 Study reported = 0.04 Not statistically significant,
p = 0.49
High Behavioral problems attributable to substance use
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.15 = 0.12 OR = 1.27 HomVEE calculated = 0.15 Not statistically significant,
p = 0.41
High Currently using marijuana
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.08 = 0.09 OR = 0.86 HomVEE calculated = -0.09 Not statistically significant,
p = 0.67
High Moderate/heavy drinker (= 3 drinks, = 3 times in 14 days)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.04 = 0.04 OR = 1.09 HomVEE calculated = 0.06 Not statistically significant,
p = 0.84
High Months between births of first and second children
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 24.51 Adjusted mean = 20.39 Mean difference = 4.12 Study reported = 0.32 Statistically significant,
p = 0.01
High Number of subsequent live births
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 0.48 Adjusted mean = 0.57 Mean difference = -0.09 Study reported = -0.13 Not statistically significant,
p = 0.18
High Number of subsequent pregnancies
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 0.85 Adjusted mean = 0.88 Mean difference = -0.03 Study reported = -0.04 Not statistically significant,
p = 0.72
High Pearlin Mastery Scale
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers Adjusted mean = 99.41 Adjusted mean = 99.31 Mean difference = 0.10 Study reported = 0.12 Not statistically significant,
p = 0.91
High Subsequent abortion
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.05 = 0.05 OR = 0.94 HomVEE calculated = -0.04 Not statistically significant,
p = 0.89
High Subsequent miscarriage
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.09 = 0.12 OR = 0.73 HomVEE calculated = -0.19 Not statistically significant,
p = 0.31
Moderate MHI
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 101.20 Adjusted mean = 99.16 Mean difference = 0.66 Study reported = -0.03 Statistically significant,
p = 0.03
Moderate Behavioral problems attributable to substance use
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.10 = 0.12 OR = 0.82 HomVEE calculated = -0.12 Not statistically significant,
p = 0.52
Moderate Moderate/heavy drinker (= 3 drinks, = 3 times in 14 days)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.03 = 0.04 OR = 0.74 HomVEE calculated = -0.21 Not statistically significant,
p = 0.54
Moderate Months between births of first and second children
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 22.20 Adjusted mean = 20.39 Mean difference = 1.81 Study reported = 0.14 Not statistically significant,
p = 0.27
Moderate Number of subsequent live births
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 0.53 Adjusted mean = 0.57 Mean difference = -0.04 Study reported = -0.06 Not statistically significant,
p = 0.57
Moderate Number of subsequent pregnancies
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 0.88 Adjusted mean = 0.88 Mean difference = 0.00 Study reported = 0.00 Not statistically significant,
p = 1.00
Moderate Pearlin Mastery Scale
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers Adjusted mean = 101.20 Adjusted mean = 99.31 Mean difference = 1.94 Study reported = 0.20 Statistically significant,
p = 0.03
Moderate Subsequent abortion
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.06 = 0.05 OR = 1.19 HomVEE calculated = 0.10 Not statistically significant,
p = 0.67
Moderate Subsequent miscarriage
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.07 = 0.12 OR = 0.50 HomVEE calculated = -0.42 Statistically significant,
p = 0.04
Moderate Currently using marijuana
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison, (Denver) 4-year follow-up 431 mothers = 0.09 = 0.09 OR = 0.94 HomVEE calculated = -0.04 Not statistically significant,
p = 0.87
Positive parenting practices
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High HOME total score
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 mothers Adjusted mean = 25.32 Adjusted mean = 25.09 Mean difference = 0.23 Study reported = 0.07 Not statistically significant,
p = 0.47
High Sensitive/responsive interaction
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 408 mothers Adjusted mean = 100.51 Adjusted mean = 98.66 Mean difference = 1.85 Study reported = 0.18 Not statistically significant,
p = 0.06
Moderate HOME total score
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 mothers Adjusted mean = 25.08 Adjusted mean = 25.09 Mean difference = -0.01 Study reported = 0.00 Not statistically significant,
p = 0.96
Moderate Sensitive/responsive interaction
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 412 mothers Adjusted mean = 100.92 Adjusted mean = 98.66 Mean difference = 2.26 Study reported = 0.23 Statistically significant,
p = 0.03
Reductions in juvenile delinquency, family violence, and crime
Rating Outcome measure Effect Sample Timing of follow-up Sample size Intervention group Comparison group Group difference Effect size Statistical significance Notes
High Any domestic violence (past 6 months)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.07 = 0.14 OR = 0.47 HomVEE calculated = -0.46 Statistically significant,
p = 0.05
High Any domestic violence (since child age 2)
FavorableUnfavorable or ambiguousNo Effect
Nurse home visitor and comparison (Denver) 4-year follow-up 424 mothers = 0.16 = 0.24 OR = 0.60 HomVEE calculated = -0.31 Not statistically significant,
p = 0.09
Moderate Any domestic violence (past 6 months)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.14 = 0.14 OR = 1.05 HomVEE calculated = 0.03 Not statistically significant,
p = 0.88
Moderate Any domestic violence (since child age 2)
FavorableUnfavorable or ambiguousNo Effect
Paraprofessional home visitor and comparison (Denver) 4-year follow-up 431 mothers = 0.22 = 0.24 OR = 0.90 HomVEE calculated = -0.06 Not statistically significant,
p = 0.72