Childhood Asthma Prevention Study (CAPS)

Model effectiveness research report last updated: 2012

Effects shown in research & outcome measure details

Child health

Findings rated high

Klinnert, M. D., Liu, A. H., Pearson, M. R., Ellison, M. C., Budhiraja, N., & Robinson, J. L. (2005). Short-term impact of a randomized multifaceted intervention for wheezing infants in low-income families. Archives of Pediatrics & Adolescent Medicine, 159(1), 75-82.

Childhood Asthma Prevention Study (CAPS)

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Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance	Notes
Cotinine level	FavorableUnfavorable or ambiguousNo Effect	12 months	Denver, Colorado sample	130 children	= 0.66	= 0.56	Mean difference = 0.10	HomeVEE calculated = 0.25	Not statistically significant, p = 0.28	footnote127 Submitted by user on Fri, 03/15/2019 - 14:29 Cotinine level outcome based on logistic regression model. Outcome from logrnormal regression model had high attrition and is not included in this report.
Functional Severity Score	FavorableUnfavorable or ambiguousNo Effect	12 months	Denver, Colorado sample	150 children	Mean = 1.03	Mean = 1.04	Mean difference = -0.01	Not available	Not Statistically significant, p = 0.60

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Outcome measure	Outcome measure description	Collection method	Properties
Cotinine level	The authors measured cotinine levels to detect environmental tobacco smoke exposure. The measure indicates the percentage of infants in whom cotinine levels, a metabolite of nicotine, were greater than 5 nanograms of cotinine per gram of creatinine.	Infant urine samples	Not applicable
Functional Severity Score	Incidence and severity of infant respiratory symptoms over the past six months.	Parent/caregiver report	Not applicable

Klinnert, M. D., Liu, A. H., Pearson, M. R., Tong, S., Strand, M, Luckow, A., & Robinson, J. L. (2007). Outcome of a randomized multifaceted intervention with low-income families of wheezing infants. Archives of Pediatrics & Adolescent Medicine, 161(8), 783-790.

Childhood Asthma Prevention Study (CAPS)

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Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance
Emergency Department Visits	FavorableUnfavorable or ambiguousNo Effect	Between 24 and 34 months	Denver, CO sample	144 children	Unadjusted mean = 18.60	Unadjusted mean = 24.30	OR = 0.85	HomeVEE calculated = 0.01	Not statistically significant, p = .72
Oral corticosteroid use	FavorableUnfavorable or ambiguousNo Effect	Between 24 and 34 months	Denver, CO sample	144 children	Unadjusted mean = 18.60	Unadjusted mean = 24.30	OR = 0.69	HomeVEE calculated = 0.01	Not statistically significant, p = .44

Show outcome measure summary

Outcome measure	Outcome measure description	Collection method	Properties
Emergency Department Visits	Percentage of child emergency department visits between three and four years of age	Review of medical records	Not applicable
Oral corticosteroid use	Percentage of children who had a course of oral corticosteroids during the previous year.	Review of medical records	Not applicable

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