Nurse-Family Partnership (NFP)®
Model effectiveness research report last updated: 2024
Effects shown in research
Child health
Findings rated high
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Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
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5-minute Apgar | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | Adjusted mean = 8.60 | Adjusted mean = 8.70 | Mean difference = -0.10 | Not available | Not statistically significant, p > 0.05 |
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Birth weight, grams | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Memphis) | 1082 children | Adjusted mean = 3032.20 | Adjusted mean = 3050.40 | Mean difference = -18.20 | Not available | Not statistically significant, p > 0.05 |
|
Breastfeeding attempted, percentage | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | % (adjusted) = 26.00 | Adjusted mean % = 16.00 | OR = 1.90 | HomVEE calculated = 0.37 | Statistically significant, p < 0.01 |
The odds ratio compares the nurse-visited group to the comparison.
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Gestational age, weeks | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | Adjusted mean = 39.00 | Adjusted mean = 39.00 | Mean difference = 0.00 | Not available | Not statistically significant, p > 0.05 |
|
Immunizations up to date, percentage | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | % (adjusted) = 70.00 | Adjusted mean % = 68.00 | OR = 1.10 | HomVEE calculated = 0.06 | Not statistically significant, p > 0.05 |
The odds ratio compares the nurse-visited group to the comparison.
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Indicated preterm delivery (percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 3.00 | Adjusted mean % = 3.00 | OR = 1.00 | HomVEE calculated = 0.00 | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
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Intrauterine growth restriction (percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 9.00 | Adjusted mean % = 9.00 | OR = 1.00 | HomVEE calculated = 0.00 | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
Low birth weight (percentage < 2500 g) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 15.00 | Adjusted mean % = 14.00 | OR = 1.10 | HomVEE calculated = 0.05 | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
Number of well-child visits | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | Adjusted mean = 4.60 | Adjusted mean = 4.80 | Mean difference = -0.20 | Not available | Not statistically significant, p > 0.05 |
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Preterm (less than 37 weeks, percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 11.00 | Adjusted mean % = 13.00 | OR = 0.80 | HomVEE calculated = -0.12 | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
|
Spontaneous preterm delivery, percentage | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 8.00 | Adjusted mean % = 9.00 | OR = 0.80 | HomVEE calculated = -0.08 | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the odds ratio.
The odds ratio compares the nurse-visited group to the comparison.
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Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Number of subsequent low birth weight newborns (< 2500 g) | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Mean = 0.12 | Mean = 0.15 | Mean difference = -0.03 | Not available | Not statistically significant, p ≥ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
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Number of subsequent neonatal intensive care unit or special care admissions | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Mean = 0.14 | Mean = 0.20 | Mean difference = -0.06 | Not available | Not statistically significant, p ≥ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
Authors report the difference in this outcome to be statistically significant, p < 0.10, which is greater than the acceptable alpha for this review (α = 0.05).
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Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Any Medicaid-paid nonbirth hospitalizations |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
1105 children | Adjusted proportion = 0.14 | Adjusted proportion = 0.20 | Difference = -0.06 | Study reported = -0.26 | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. The study reported this finding was statistically significant (p = 0.01) prior to a multiple comparisons adjustment. |
At risk of being overweight (%) |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
747 children | Adjusted proportion = 0.29 | Adjusted proportion = 0.34 | Difference = -0.05 | Study reported = -0.13 | Not statistically significant, p ≥ 0.05 |
Negative effect is favorable to the intervention. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Duration of breastfeeding |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
918 children | Adjusted mean = 4.40 | Adjusted mean = 4.60 | Difference = -0.20 | Not available | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Normal weight (%) |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
747 children | Adjusted proportion = 0.59 | Adjusted proportion = 0.54 | Difference = 0.05 | Study reported = 0.13 | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Number of Medicaid-paid immunizations |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
895 children | Adjusted mean = 6.90 | Adjusted mean = 7.50 | Difference = -0.60 | Not available | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Primary care provider for the child (%) |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
939 children | Adjusted proportion = 0.88 | Adjusted proportion = 0.88 | Difference = 0.00 | Study reported = -0.02 | Not statistically significant, p ≥ 0.05 |
The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Underweight (%) |
FavorableUnfavorable or ambiguousNo Effect |
15-month follow-up |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States,full sample |
747 children | Adjusted proportion = 0.11 | Adjusted proportion = 0.12 | Difference = -0.01 | Study reported = -0.04 | Not statistically significant, p ≥ 0.05 |
Negative effect is favorable to the intervention. The statistical significance after adjusting for multiple comparisons is reported; precise p-values are not available. |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Admitted to neonatal intensive care unit (%) |
FavorableUnfavorable or ambiguousNo Effect |
Birth |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1854 infants | Not reported | Not reported | Difference = 0.01 | Not available | Not statistically significant, p= 0.68 |
|
Any emergency department visits (%) |
FavorableUnfavorable or ambiguousNo Effect |
12 months old |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1854 infants | Not reported | Not reported | Difference = 0.00 | Not available | Not statistically significant, p= 0.90 |
|
Any nonbirth hospitalizations (%) |
FavorableUnfavorable or ambiguousNo Effect |
12 months old |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1854 infants | Not reported | Not reported | Difference = -0.01 | Not available | Not statistically significant, p= 0.52 |
|
Average number of well-child office visits |
FavorableUnfavorable or ambiguousNo Effect |
12 months old |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1854 infants | Not reported | Not reported | Difference = -0.16 | Not available | Not statistically significant, p= 0.37 |
|
Low birth weight (< 2,500 grams; %) |
FavorableUnfavorable or ambiguousNo Effect |
Birth |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1714 infants | Not reported | Not reported | Difference = 0.00 | Not available | Not statistically significant, p= 0.87 |
Negative effect is favorable to the intervention. |
Preterm birth (< 37 weeks; %) |
FavorableUnfavorable or ambiguousNo Effect |
Birth |
NFP vs. Resource referral RCT (MIHOPE-Strong Start), 2012-2015, United States, full sample |
1715 infants | Not reported | Not reported | Difference = 0.02 | Not available | Not statistically significant, p= 0.24 |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Adverse birth outcome composite |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4966 children | Adjusted proportion = 0.27 Infants | Adjusted proportion = 0.26 Infants | Mean difference = 0.01 | Study reported = 0.02 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Extremely preterm birth |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Adjusted proportion = 0.01 Infants | Adjusted proportion = 0.01 Infants | Mean difference = 0.00 | Study reported = 0.00 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Large for gestational age |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Adjusted proportion = 0.05 Infants | Adjusted proportion = 0.06 Infants | Mean difference = -0.01 | Study reported = -0.11 | Not statistically significant, p= ≥0.05 |
|
Mean birth weight (in grams) |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Adjusted mean = 3086.10 Infants | Adjusted mean = 3093.90 Infants | Mean difference = -7.80 | HomVEE calculated = -0.01 | Not statistically significant, p = 0.67 |
Statistical significance is based on HomVEE calculations. |
Mean gestational age (in weeks) |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Adjusted mean = 38.20 Infants | Adjusted mean = 38.10 Infants | Mean difference = 0.10 | HomVEE calculated = 0.04 | Not statistically significant, p = 0.15 |
Statistical significance is based on HomVEE calculations. |
Neonatal morbidity |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Unadjusted proportion = 0.10 Infants | Unadjusted proportion = 0.09 Infants | Mean difference = 0.01 | Study reported = 0.09 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Overnight NICU stay |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4543 children | Adjusted proportion = 0.08 Infants | Adjusted proportion = 0.09 Infants | Mean difference = -0.01 | Study reported = -0.06 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Very low birth weight |
FavorableUnfavorable or ambiguousNo Effect |
Child's birth |
NFP vs. usual care RCT, South Carolina 2016-2021, full sample |
4932 children | Adjusted proportion = 0.02 Infants | Adjusted proportion = 0.03 Infants | Mean difference = -0.01 | Study reported = -0.17 | Not statistically significant, p= ≥0.05 |
Negative effect is favorable to the intervention. |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
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Number of Medicaid-paid child emergency department visits (fixed effect random slope analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.50 | Not available | Statistically significant, p= 0.02 |
Number of Medicaid-paid child emergency department visits (restricted maximum likelihood analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.50 | Not available | Statistically significant, p= 0.03 |
Number of Medicaid-paid child emergency department visits (split-sample analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.50 | Not available | Statistically significant, p= 0.01 |
Number of Medicaid-paid well-child visits (fixed effect random slope analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.30 | Not available | Not statistically significant, p= 0.43 |
Number of Medicaid-paid well-child visits (restricted maximum likelihood analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.20 | Not available | Not statistically significant, p= 0.45 |
Number of Medicaid-paid well-child visits (split-sample analysis) |
FavorableUnfavorable or ambiguousNo Effect |
15 months old |
NFP vs. Resource referral RCT (MIHOPE), 2012-2015, United States, full sample |
895 children | Not reported | Not reported | Difference = -0.30 | Not available | Not statistically significant, p= 0.10 |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
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Night awake (mother-reported number of episodes last 2 weeks | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy and comparison (Elmira) | 164 children | Adjusted mean = 3.25 | Adjusted mean = 2.83 | Mean difference = 0.42 | Not available | Statistical significance not reported |
Night awake (mother-reported number of episodes last 2 weeks | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 163 children | Adjusted mean = 2.69 | Adjusted mean = 2.83 | Mean difference = -0.14 | Not available | Not statistically significant, p > 0.05 |
Number of emergency room visits (first year of life) | FavorableUnfavorable or ambiguousNo Effect |
1-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 205 children | Adjusted mean = 1.12 | Adjusted mean = 1.02 | Mean difference = 0.10 | Not available | Statistical significance not reported |
Number of emergency room visits (first year of life) | FavorableUnfavorable or ambiguousNo Effect |
1-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 223 children | Adjusted mean = 0.74 | Adjusted mean = 1.02 | Mean difference = -0.28 | Not available | Statistically significant, p < 0.05 |
Number of emergency room visits (second year of life) | FavorableUnfavorable or ambiguousNo Effect |
2-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 185 children | Adjusted mean = 1.04 | Adjusted mean = 1.09 | Mean difference = -0.05 | Not available | Statistical significance not reported |
Number of emergency room visits (second year of life) | FavorableUnfavorable or ambiguousNo Effect |
2-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 196 children | Adjusted mean = 0.74 | Adjusted mean = 1.09 | Mean difference = -0.35 | Not available | Statistically significant, p < 0.01 |
Resist eating (mother-reported number of episodes last 2 weeks) | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy and comparison (Elmira) | 164 children | Adjusted mean = 2.01 | Adjusted mean = 1.72 | Mean difference = 0.29 | Not available | Statistical significance not reported |
Resist eating (mother-reported number of episodes last 2 weeks) | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 163 children | Adjusted mean = 2.29 | Adjusted mean = 1.72 | Mean difference = 0.57 | Not available | Statistically significant, p < 0.01 |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
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Number of days hospitalized (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 0.43 | Adjusted mean = 0.31 | Mean difference = 0.12 | Not available | Statistical significance not reported | |
Number of days hospitalized (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 0.49 | Adjusted mean = 0.31 | Mean difference = 0.18 | Not available | Statistically significant, p ≤ 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
Number of emergency department visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 1.24 | Adjusted mean = 1.53 | Mean difference = -0.29 | Not available | Statistical significance not reported | |
Number of emergency department visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 1.00 | Adjusted mean = 1.53 | Mean difference = -0.53 | Not available | Statistically significant, p ≤ .01 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
|
Number of hospital admissions (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 0.11 | Adjusted mean = 0.11 | Mean difference = 0.00 | Not available | Statistical significance not reported | |
Number of hospital admissions (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 0.14 | Adjusted mean = 0.11 | Mean difference = 0.03 | Not available | Not statistically significant, p > 0.05 |
Statistical significance reported on authors’ calculations of the log-incidence difference.
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Number of scheduled health supervision visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 1.27 | Adjusted mean = 1.56 | Mean difference = -0.29 | Not available | Statistical significance not reported | |
Number of scheduled health supervision visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 1.26 | Adjusted mean = 1.56 | Mean difference = -0.30 | Not available | Not statistically significant, p > 0.05 |
|
Number of scheduled health supervision visits with problems (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 5.18 | Adjusted mean = 6.72 | Mean difference = -1.54 | Not available | Statistical significance not reported | |
Number of scheduled health supervision visits with problems (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 6.24 | Adjusted mean = 6.72 | Mean difference = -0.48 | Not available | Not statistically significant, p > 0.05 |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
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Subsequent NICU/special care admission (rate per subsequent birth) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 18.00 | Adjusted mean % = 23.00 | OR = -0.72 | HomVEE calculated = -0.20 | Not statistically significant, p = 0.14 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
Subsequent low birth weight newborn (rate per subsequent birth) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 11.00 | Adjusted mean % = 16.00 | OR = -0.69 | HomVEE calculated = -0.22 | Not statistically significant, p = 0.16 |
Statistical significance reported on authors’ calculations of the odds ratio.
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Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Number of infant and childhood deaths among firstborn children (birth–9 years) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | per 1,000 = 4.50 per 1,000 | per 1,000 = 20.08 per 1,000 | OR = 0.22 | Not available | Not statistically significant, p = 0.80 |
Statistical significance reported on authors’ calculations of the odds ratio.
|
Number of subsequent low birth weight newborns (0–9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.18 | Adjusted mean = 0.27 | Mean difference = -0.09 | Not available | Not statistically significant, p = 0.07 |
Statistical significance reported on authors’ calculation of incidence ratio.
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Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Subsequent low birth weight newborns | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.06 | = 0.08 | OR = 0.75 | HomVEE calculated = -0.17 | Not statistically significant, p = 0.45 |
Subsequent special care admissions | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.06 | = 0.08 | OR = 0.66 | HomVEE calculated = -0.26 | Not statistically significant, p = 0.27 |
Findings rated moderate
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Birth weight (grams) | FavorableUnfavorable or ambiguousNo Effect |
Birth | NFP-trained nurse visitors and comparison nurse visitors | 156 children | Mean = 3.00 | Mean = 3.00 | Mean difference = 164.26 | HomVEE calculated = 0.29 | Not reported |
Gestational age (months) | FavorableUnfavorable or ambiguousNo Effect |
Birth | NFP-trained nurse visitors and comparison nurse visitors | 154 children | Mean = 38.88 | Mean = 38.92 | Mean difference = -0.04 | HomVEE calculated = -0.02 | Not reported |
Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
20 year child mortality rate - all causes (Nurse home visits during pregnancy and infancy vs. developmental screening comparison) | FavorableUnfavorable or ambiguousNo Effect |
20 years | Nurse home visits during pregnancy and infancy vs. developmental screening comparison (Memphis) | 708 mother/child dyads | Unadjusted mean = 0.01 | Unadjusted mean = 0.03 | Mean difference = -0.02 | HomVEE calculated = -0.68 | Not statistically significant, p = 0.11 | Negative value is favorable to the intervention.
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20 year child mortality rate - preventable cause (Nurse home visits during pregnancy and infancy vs. developmental screening comparison) | FavorableUnfavorable or ambiguousNo Effect |
20 years | Nurse home visits during pregnancy and infancy vs. developmental screening comparison (Memphis) | 708 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.02 | Mean difference = -0.02 | Not available | Statistically significant, p = 0.04 | Negative value is favorable to the intervention.
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Show findings details
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
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Subsequent low birth weight newborns | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional. home visitor and comparison (Denver) | 431 mothers | = 0.03 | = 0.08 | OR = 0.34 | HomVEE calculated = -0.64 | Statistically significant, p = 0.03 |
Subsequent special care admissions | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.05 | = 0.08 | OR = 0.54 | HomVEE calculated = -0.38 | Not statistically significant, p = 0.13 |